3MB-PP1 is a bulky purine analog and a Polo-like kinase 1 (Plk1) inhibitor. In cells expressing analog-sensitive Plk1 alleles, 3MB-PP1 blocks mitotic progression and cell division arise by targeting Plk1. 3MB-PP1 specifically inhibits analog-sensitive Ssn3 (Cdk8). 3MB-PP1 inhibits Leu93 Mutant Zipper-interacting protein kinase with IC50 of 2 µM. 3MB-PP1 can be used for the research of cell division and hypha formation of Candida albicans.
Molecular Weight:
295.38
Purity:
99.96%
CAS Number:
[956025-83-5]
Formula:
C17H21N5
Target:
CDK|||DAPK|||PLK
T21678
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