CCT018159 is a 3,4-diarylpyrazole resorcinol, an ATP-competitive HSP90ATPase inhibitor that inhibits human Hsp90beta and yeast Hsp90 with IC50s of 3.2 and 6.6 µM, respectively.CCT018159 inhibits key endothelial and tumor cell functions associated with invasion and angiogenesis. CCT018159 caused cellular inhibition associated with G1 phase block and induced apoptosis.
Molecular Weight:
352.38
Purity:
99.79%
CAS Number:
[171009-07-7]
Formula:
C20H20N2O4
Target:
Apoptosis|||HSP
T21872
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