UMB-32 is a potent and selective BRD4 inhibitor, demonstrating an affinity for BRD4 with a dissociation constant (K d) of 550 nM and an inhibitory concentration 50 (IC 50) of 637 nM. Moreover, UMB-32 exhibits effectiveness against TAF1, a bromodomain-containing transcription factor [1].
Molecular Weight:
361.44
CAS Number:
[1635437-39-6]
Formula:
C21H23N5O
Target:
Epigenetic Reader Domain|||Others
T21920
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