BX 513 hydrochloride (VUF 2274 HCl) is a selective CCR1 antagonist (Ki=0.04 µM) that concentration-dependently inhibits CCL18-induced acidification in THP-1 monocytes and suppresses RANTES- and CCL18-induced chemotaxis in peripheral blood mononuclear cells (PBMCs).
Molecular Weight:
481.46
Purity:
99.95%
CAS Number:
[1216540-18-9]
Formula:
C28H30Cl2N2O
Target:
CCR
T22055
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