CHMFL-ABL-053 (Compound 18a) is a potent, selective, and orally available inhibitor of BCR-ABL, SRC, and p38 kinases, with IC50 values of 70, 90, and 62 nM against ABL1, SRC, and p38, respectively. CHMFL-ABL-053 is a potentially useful drug candidate for Chronic Myeloid Leukemia (CML) [1].
Molecular Weight:
549.55
CAS Number:
[1808287-83-3]
Formula:
C28H26F3N7O2
Target:
Others|||Bcr-Abl|||Src|||p38 MAPK
T22067
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