WWL123 is a potent and selective ABHD6 inhibitor (IC50=430 nM). WWL123 crosses the blood-brain-barrier and inhibits ABHD6 in brain parenchyma. ABHD6 blockade by WWL123 exerts an antiepileptic effect in Pentylenetetrazole (PTZ)-induced epileptiform seizures and spontaneous seizures in R6/2 mice.
Molecular Weight:
436.5
Purity:
99.62%
CAS Number:
[1338575-41-9]
Formula:
C28H24N2O3
Target:
MAGL
T22171
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