3PO is a small-molecule inhibitor of PFKFB3 (IC50: 22.9 µM), inhibiting the proliferation of several human malignant hematopoietic and adenocarcinoma cell lines (IC50: 1.4-24 µM). It suppresses glucose uptake, and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+, and NADH.
Molecular Weight:
210.23
Purity:
99.67%
CAS Number:
[18550-98-6]
Formula:
C13H10N2O
Target:
Autophagy|||Glucokinase
T22223
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