Lifirafenib (Beigene-283) is a potent inhibitor of RAF family kinases and EGFR in biochemical assays with IC50 of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant respectively.
Molecular Weight:
478.42
Purity:
98.25%
CAS Number:
[1446090-79-4]
Formula:
C25H17F3N4O3
Target:
EGFR|||Raf
T22272
* VAT and and shipping costs not included. Errors and price changes excepted