AMG 487 is an effective and selective antagonist of chemokine receptor 3. AMG 487 inhibited CXCR3-mediated cell migration induced by three CXCR3 chemokines, IP-10, ITAC and MIG (IC50: 8, 15 and 36 nM, respectively).
Molecular Weight:
603.59
Formula:
C32H28F3N5O4
Target:
Others|||CXCR
T22477
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