EC 144, a second-generation selective inhibitor of Hsp90 (heat shock protein 90), inhibits tumor growth with an IC50= 1.1 nM for Hsp90alpha and an EC50 = 14 nM for degradation of Her-2 in MCF-7 cells.
Molecular Weight:
413.9
CAS Number:
[911397-80-3]
Formula:
C21H24ClN5O2
Target:
HSP
T22758
T22758
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