Lenalidomide hemihydrate is a derivative of Thalidomide, an orally active immunomodulator that acts as a molecular gel. It is a ligand for the ubiquitin E3 ligase cereblon, which selectively ubiquitinates and degrades two lymphoid transcription factors, IKZF1 and IKZF3, via the CRBN-CRL4 ubiquitin ligase.
Molecular Weight:
268.28
Purity:
>99.99%
CAS Number:
[847871-99-2]
Formula:
C13H13N3O3.1/2H2O
Target:
IKZF|||TNF|||Molecular Glues|||Ligands for E3 Ligase|||Apoptosis
T22922
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