N,N-Dimethylsphingosine, an endogenous metabolite, is a potent competitive sphingosine kinase (SphK) inhibitor that selectively inhibits sphingosine phosphorylation without affecting its N-acylation.DMS is elevated in models of neuropathic pain, and may mediate mechanical nociception by increasing the release of IL-1beta and MCP-1.
Molecular Weight:
327.55
CAS Number:
[119567-63-4]
Formula:
C20H41NO2
Target:
S1P Receptor
T23045
T23045
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