CHIR-99021 (CT99021) is an activator of the Wnt/beta-catenin signaling pathway and a GSK-3alpha/beta inhibitor (IC50=10/6.7 nM) with selective and oral activity.CHIR-99021 induces cellular autophagy, which enhances self-renewal in mouse and human embryonic stem cells.
Molecular Weight:
465.34
Purity:
95%
CAS Number:
[252917-06-9]
Formula:
C22H18Cl2N8
Target:
Autophagy|||Wnt/beta-catenin|||GSK-3
T2310
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