CHIR-99021 HCl, CAS [[1797989-42-4]]

Product Overview

• Article Name: CHIR-99021 HCl, CAS [[1797989-42-4]]
• Biozol Catalog Number: TGM-T2310L
• Supplier Catalog Number: T2310L
• Alternative Catalog Number: TGM-T2310L-1MLX10MM(INDMSO),TGM-T2310L-1MG,TGM-T2310L-2MG,TGM-T2310L-5MG,TGM-T2310L-10MG,TGM-T2310L-25MG,TGM-T2310L-50MG,TGM-T2310L-100MG,TGM-T2310L-200MG,TGM-T2310L-500MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: CT99021 HCl , Laduviglusib HCl

Product Description

CHIR-99021 HCl (Laduviglusib HCl) is a highly potent and selective inhibitor of GSK-3alpha/beta, with IC50 values of 10 nM and 6.7 nM respectively. It demonstrates remarkable selectivity for GSK-3, with over 500-fold selectivity over CDC2, ERK2, and other protein kinases. Additionally, CHIR-99021 HCl serves as a robust activator of the Wnt/beta-catenin signaling pathway. Moreover, it exhibits the ability to enhance self-renewal in both mouse and human embryonic stem cells. Furthermore, CHIR-99021 HCl induces autophagy [1] [2] [3].

Product Properties

• Molecular Weight: 501.8
• Purity: 98.44%
• CAS Number: [1797989-42-4]
• Formula: C22H19Cl3N8
• Target: Autophagy|||Wnt/beta-catenin|||GSK-3

Images

T2310L