PB28 dihydrochloride is a selective and potent sigma 2 (sigma2) receptor agonist and sigma1 receptor antagonist with anti-SARS-CoV-2 activity and anti-tumor activity, which inhibits cell proliferation and invasion and suppresses SKF by modulating the PI3K-AKT-mTOR signaling pathway in renal cancer. It inhibits cell proliferation and invasion by regulating the PI3K-AKT-mTOR signaling pathway in renal cancer, inhibits calcium release from the endoplasmic reticulum of SK-N-SH neuroblastoma cells, and induces non-caspase-dependent apoptosis.
Molecular Weight:
443.49
Purity:
99.97%
CAS Number:
[172907-03-8]
Formula:
C24H40Cl2N2O
Target:
Apoptosis|||Sigma receptor|||SARS-CoV
T23122
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