PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. It also inhibits the PDGFR, EGFR, and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, and 44 nM, respectively.
Molecular Weight:
532.51
Purity:
99.23%
CAS Number:
[192705-80-9]
Formula:
C26H35Cl2N7O
Target:
TGF-beta/Smad|||EGFR|||FGFR|||PDGFR|||Src
T23127
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