Ro 32-0432 is a selective, ATP-competitive, orally active pan-PKC inhibitor exhibiting inhibitory effects on PKCalpha, PKCbetaI, PKCbetaII, PKCgamma, and PKCepsilon. It blocks T-cell activation and may be employed in inflammatory and immune disorders. (S)-Ro 32-0432 hydrochloride is a GRK5 (G protein-coupled receptor kinase 5) inhibitor that alleviates nicotine withdrawal symptoms.
Molecular Weight:
452.55
CAS Number:
[151342-35-7]
Formula:
C28H28N4O2
Target:
PKC|||GRK
T23244
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