5-Iodowillardiine is a selective agonist for specific kainate receptor subunits that robustly activates GluK1 (GluR5) and GluK5 (KA2)-containing receptors while displaying minimal activity at AMPA receptors and no measurable agonism toward GluK2 (GluR6) subunits. Despite its excitotoxic neurotoxic activity in vivo, 5-Iodowillardiine remains a powerful experimental tool for dissecting kainate receptor subtype distribution, synaptic function, and excitatory neurotransmission in the brain and spinal cord.
Molecular Weight:
325.06
CAS Number:
[140187-25-3]
Formula:
C7H8IN3O4
Target:
Others|||GluR|||iGluR
T23295
* VAT and and shipping costs not included. Errors and price changes excepted