VU-29 is a positive allosteric mGlu5 receptor modulator with an EC50 of 9 nM and a Ki of 244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes [EC50: rmGluR1/rmGluR2=557 nM/1.5 µM, hmGluR4=154 nM].
Molecular Weight:
384.39
Purity:
99.63%
CAS Number:
[890764-36-0]
Formula:
C22H16N4O3
Target:
GluR
T23515
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