Edoxaban (Lixiana) (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with K i s of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and is able to be used for stroke prevention. Edoxaban is a also weak inhibitor of thrombin and factor IXabeta (FIXa), with K i s of 6.00 µM and 41.7 µM, respectively, exhibits >10 000-fold selectivity for FXa. Edoxaban has antithrombotic properties and is potential for thromboembolic diseases treatment [1] [2] [3].
Molecular Weight:
548.06
Purity:
99.71%
CAS Number:
[480449-70-5]
Formula:
C24H30ClN7O4S
Target:
Factor Xa|||Thrombin
T2368L
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