Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRalpha, VEGFR2, FGFR1, and Src, respectively.
Molecular Weight:
569.02
Purity:
>99.99%
CAS Number:
[1114544-31-8]
Formula:
C29H28ClF3N6O
Target:
Src|||PDGFR|||Bcr-Abl|||Autophagy|||VEGFR|||FGFR
T2372L
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