BMS-986169 is a high-affinity and selective negative allosteric modulator of the NMDA receptor GluN2B subunit, with an IC50 of 24 nM in oocytes, and exhibits antidepressant-like activity in mice, making it a potential treatment for treatment-resistant depression.
Molecular Weight:
382.47
Purity:
97.61%
CAS Number:
[1801151-08-5]
Formula:
C23H27FN2O2
Target:
Others|||NMDAR|||iGluR
T23808
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