CLK1/2-IN-3 (Cpd-3) is a potent and selective CLK1 and CLK2 inhibitor with antiproliferative activity and inhibits the activities of CLK1, CLK2, SRPK1, SRPK2, and SRPK3.CLK1/2-IN-3 induces nuclear speckle enlargement, which induces S6K pre-mRNA-selective splicing and subsequent inhibition of cell growth of multiple cancer cell types. cancer cell types cell growth.
Molecular Weight:
375.42
Purity:
99.04%
CAS Number:
[1005784-60-0]
Formula:
C21H21N5O2
Target:
Serine/threonin kinase|||CDK
T23897
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