Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist (IC50: 0.26 nM). Upon hydrolysis to candesartan during gastrointestinal absorption, it selectively competes with angiotensin II for binding to the angiotensin II receptor subtype 1 (AT1) in vascular smooth muscle, blocking angiotensin II-mediated vasoconstriction and inducing vasodilatation.
Molecular Weight:
610.66
Purity:
>99.99%
CAS Number:
[145040-37-5]
Formula:
C33H34N6O6
Target:
RAAS|||Apoptosis
T2400
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