Bromfenac monosodium salt sesquihydrate , Bromfenac sodium sesquihydrate
Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is the sodium salt form of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory properties. Upon ophthalmic administration, bromfenac binds to and inhibits cyclooxygenase II (COX II), an enzyme that converts arachidonic acid to cyclic endoperoxides, which are prostaglandin (PG) precursors. By inhibiting PG formation, bromfenac prevents PG-induced inflammation, vasodilation, leukocytosis, disruption of the blood-aqueous humor barrier, increased vascular permeability, and elevated intraocular pressure (IOP).
Molecular Weight:
383.17
Purity:
91.85%
CAS Number:
[120638-55-3]
Formula:
C15H12BrNO33/2H2ONa
Target:
COX
T2403
T2403
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