Nedaplatin (NSC-375101D) is a derivative of cisplatin and DNA damage agent for tumor colony forming units (IC50: 94 µM). Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand, nedaplatin forms reactive platinum complexes that bind to nucleophilic groups in DNA, resulting in intrastrand and interstrand DNA cross-links, apoptosis and cell death.
Molecular Weight:
303.17
Purity:
>99.99%
CAS Number:
[95734-82-0]
Formula:
C2H8N2O3Pt
Target:
DNA/RNA Synthesis
T2410
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