PF-04859989 is a brain-penetrable irreversible inhibitor of kynurenine amino transferase II. PF-04859989 is ~1000-fold selective for KAT II over human KAT I, KAT III, and KAT IV. PF-04859989 has IC50 values of 23 nM for hKAT II and 263 nM for rKAT II.
Molecular Weight:
178.19
CAS Number:
[34783-48-7]
Formula:
C9H10N2O2
Target:
Others
T24617
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