SKA-111 is a selective calcium-activated potassium phannel (potassium phannel ) KCa3.1 activator that induces membrane hyperpolarization in porcine endothelial cells.SKA-111 binds to the interface between the CaM N-valve and the S4-S5 junction and ameliorates Bradykinin-induced dilation of coronary arteries in the isolated rat heart, which can be used for the study of cardiovascular diseases. study of cardiovascular diseases.
Molecular Weight:
214.29
Purity:
99.79%
CAS Number:
[1369170-24-0]
Formula:
C12H10N2S
Target:
Potassium Channel
T24799
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