SP-100030 is a dual inhibitor of NF-kappaB and activator protein-1 (AP-1), demonstrating potent inhibition with IC50 values of 50 nM for both. It effectively reduces the production of IL-2, IL-8, and TNF-alpha in Jurkat and other T cell lines. Additionally, SP-100030 has been shown to decrease the severity of murine collagen-induced arthritis (CIA).
Molecular Weight:
437.65
Purity:
99.57%
CAS Number:
[154563-54-9]
Formula:
C14H5ClF9N3O
Target:
NF-kappaB
T24816
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