(Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 µM), 20-fold more selective for VEGFR over PDGFRbeta, no inhibition for FGFR, InsR, and EGFR. (Z)-Semaxinib is a quinolone derivative with potential antineoplastic activity.
Molecular Weight:
238.28
Purity:
95%
CAS Number:
[194413-58-6]
Formula:
C15H14N2O
Target:
c-Met/HGFR|||VEGFR
T2496
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