ARN-6039, an orally available inverse agonist of RORgamma, targets Autoimmune Neuroinflammatory Demyelinating Disease. Its efficacy was demonstrated in a RORgamma-activated IL-17A Prom/LUCPorter assay in HEK 293 cells (360 nM) and in IL-17 release from CD4+T cell assays (220 nM).
Molecular Weight:
406.4
CAS Number:
[1675206-11-7]
Formula:
C21H21F3N2O3
Target:
ROR|||Others
T25109
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