Filanesib (ARRY-520) targets the kinesin spindle protein (KSP) with potential antineoplastic activity. ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during the mitotic phase, and consequently cell death in tumor cells that are actively dividing.
Molecular Weight:
534.5
CAS Number:
[1781834-99-8]
Formula:
C22H23F5N4O4S
Target:
Others|||Kinesin
T25418
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