GS-9191 is a potent inhibitor of DNA polymerase alpha and ß , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , which penetrates the skin and is metabolized in the epithelium to an active nucleoside triphosphate analogue.GS-9191 has antiproliferative activity and reduces the size of papillomas in a dose-related manner.GS-9191 may be useful in the treatment of HPV-induced lesions.
Molecular Weight:
734.82
Purity:
97.83%
CAS Number:
[859209-84-0]
Formula:
C37H51N8O6P
Target:
DNA/RNA Synthesis|||Virus Protease|||Apoptosis
T25466
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