R75251 , Liarozole hydrochloride , R 75251 , R-75251
Liarozole HCl is a benzimidazole derivative with antineoplastic activity. As a retinoic acid metabolism blocking agent, liarozole inhibits CYP450-dependent all-trans-retinoic acid (ATRA)-4-hydroxylase, leading to an increase in endogenous ATRA production, inhibition of cell proliferation, and induction of cell differentiation. It also inhibits aromatase.
Molecular Weight:
345.23
CAS Number:
[145858-50-0]
Formula:
C17H14Cl2N4
Target:
Others|||Retinoid Receptor|||Cytochromes P450
T25716L
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