GSK2606414 is a cell-permeable and orally active protein kinase R-like endoplasmic reticulum kinase(PERK)inhibitor with IC50 of 0.4 nM. GSK2606414 inhibits PERK activation in cells and suppresses the growth of human tumor xenografts in mice.
Molecular Weight:
451.44
Purity:
98.00%
CAS Number:
[1337531-36-8]
Formula:
C24H20F3N5O
Target:
PERK|||Autophagy|||Apoptosis
T2614
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