LGK974 (NVP-LGK974) is an effective and selective PORCN inhibitor and inhibits Wnt signaling (IC50: 0.4 nM) in TM3 cells. It has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cell Carcinoma, Head And Neck.
Molecular Weight:
396.44
Purity:
98%
CAS Number:
[1243244-14-5]
Formula:
C23H20N6O
Target:
Porcupine
T2618
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