Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1, leading to down-regulation of Hedgehog signaling. Triparanol suppresses human tumor growth and is an antilipemic agent with high ophthalmic toxicity.
Molecular Weight:
438
Purity:
99.72%
CAS Number:
[78-41-1]
Formula:
C27H32ClNO2
Target:
Hedgehog/Smoothened|||Apoptosis
T26296
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