A 80915A is A semi-naphthoquinone antibiotic from Streptomyces aculeolatus. It is a potent inhibitor of gastric (H(+)-K+)-ATPase. Inhibition by A80915A is dependent on the conformation of gastric (H(+)-K+)-ATPase, potassium slows the rate of inhibition by converting the enzyme to a conformation where the drug binding site is not as accessible.
Molecular Weight:
529.88
CAS Number:
[127875-60-9]
Formula:
C26H31Cl3O5
Target:
Others|||Proton pump|||ATPase
T26450
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