Acanthoic acid is a pimaradiene diterpene isolated from Acanthopanax koreanum with anti-inflammatory activities. Acanthoic acid downregulates LPS-induced IL-1beta, IL-6 and TNF-alpha production in BALF, attenuates lung histopathologic changes, and inhibits inflammatory cytokines by stopping IL-1beta, IL-6 and TNF-alpha production and NF-kappaB activation in LPS-stimulated alveolar macrophages.
Molecular Weight:
302.45
CAS Number:
[119290-87-8]
Formula:
C20H30O2
T26545
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