AG-7404 is a potent protease inhibitor with anti-poliovirus activity. AG-7404 was active against all virus with EC50 values ranging from 0.080 to 0.674 µM. AG-7404 was fully active against V-073-resistant variants with EC50 values ranging from 0.218 to 0.819 µM, compared to values ranging from 0.202 to 0.407 µM for the V-073-susceptible parental strains.
Molecular Weight:
523.54
CAS Number:
[343565-99-1]
Formula:
C26H29N5O7
Target:
Virus Protease|||Others
T26574
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