Azadirone is a limonoid tetranortriterpene. Azadirone can sensitize cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through ROS-ERK-CHOP-mediated up-regulation of DR4 and DR5 signaling, down-regulation of cell survival proteins, and up-regulation of proapoptotic proteins.
Molecular Weight:
245.23
CAS Number:
[30002-86-9]
Formula:
C9H15N3O5
Target:
Bcl-2 Family|||Parasite|||Others|||TNF
T26709
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