Bisnorcymserine is a reversible inhibitor of butyrylcholinesterase. The leaving group, bisnoreseroline, interacts in a non-covalent way with Ser(200) and His(440), disrupting the existing interactions within the catalytic triad, and it stacks with Trp(84) at the bottom of the gorge, giving rise to an unprecedented hydrogen-bonding contact.
Molecular Weight:
351.44
CAS Number:
[219920-81-7]
Formula:
C21H25N3O2
Target:
Others|||Cholinesterase (ChE)
T26827
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