GSK-7227, a novel compound representing a novel class of peroxisome proliferator-activated receptor delta (PPARdelta) partial agonists, demonstrates potent partial agonistic activity by upregulating the expression of PPARdelta target genes, specifically carnitine palmitoyltransferase 1a (CPT1a) and pyruvate dehydrogenase kinase 4 (PDK4), in cultured skeletal muscle cells, indicating its potential role in modulating skeletal muscle metabolism and energy homeostasis.
Molecular Weight:
478.52
Purity:
99.17%
CAS Number:
[1067214-81-6]
Formula:
C25H22N2O6S
Target:
Dehydrogenase|||PDK|||CPT|||PPAR
T27489
T27489
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