iNUB is a selective small-molecule inhibitor of NEMO-ubiquitin binding that suppresses TNFalpha-induced NF-kappaB signaling, while exhibiting selective cytotoxicity toward IKK/NF-kappaB-dependent activated B-cell-like diffuse large B-cell lymphoma (ABC-DLBCL), making it a valuable research tool for dissecting NF-kappaB pathway dependency and targeted cancer signaling vulnerabilities.
Molecular Weight:
384.38
Purity:
98.81%
CAS Number:
[352336-00-6]
Formula:
C24H16O5
Target:
Others
T27615
T27615
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