ITH-12575 is an inhibitor of the mitochondrial Na/Ca exchanger (mNCX) that modulates mitochondrial calcium homeostasis, and at low micromolar concentrations ITH-12575 reduces Ca influx through CALHM1 channels, supporting its use in studies of mitochondrial signaling, neuronal excitability, calcium-dependent metabolism, and neurodegenerative disease mechanisms.
Molecular Weight:
331.86
Purity:
99.53%
CAS Number:
[1802013-08-6]
Formula:
C18H18ClNOS
Target:
Calcium Channel
T27639
T27639
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