Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-in ammatory, immunomodulatory, and anti-bacterial activities. It can effectively attenuate neuropathic pain in CCI rats by inhibiting the activation of p38 MAPK and NF-kappaB signaling pathways in spinal cord. It can inhibit NMDA receptor current and persistent sodium current, and inhibit the TNF-alpha level, the IL-1beta production, and cysteine-aspartic acid protease (caspase)-1 activity.
Molecular Weight:
780.98
Purity:
99.88%
CAS Number:
[20736-09-8]
Formula:
C42H68O13
Target:
NF-kappaB|||Liver X Receptor|||Antibacterial
T2768
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