NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner.
Molecular Weight:
240.68
Purity:
99.64%
CAS Number:
[88039-46-7]
Formula:
C12H13ClO3
Target:
NOD-like Receptor (NLR)|||NOD
T28178
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