ONO 1301 is a prostaglandin I2 mimetic compound with inhibitory activity against thromboxane A2 synthase, and it suppresses pancreatic fibrosis in the DBTC-induced chronic pancreatitis model by inhibiting monocyte activity through both direct effects of ONO 1301 and induction of hepatocyte growth factor. ONO 1301 also promoting HGF synthesis and elevating intracellular cyclic AMP levels via IP-receptor signaling, highlighting its therapeutic relevance in fibrotic disease and inflammation research.
Molecular Weight:
428.48
Purity:
0.9891
CAS Number:
[176391-41-6]
Formula:
C26H24N2O4
Target:
Others
T28240
* VAT and and shipping costs not included. Errors and price changes excepted