ONO-0300302 is a slow tight binding LPA1 antagonist (IC50: 0.16 nM) used to treat Benign Prostatic Hyperplasia. ONO-0300302 inhibits significantly an LPA-induced increase of intraurethral pressure (IUP) in rat (3 mg/kg, p.o.) and dog (1 mg/kg, p.o.) over 12 h.
Molecular Weight:
477.59
CAS Number:
[856689-51-5]
Formula:
C29H35NO5
Target:
LPL Receptor|||Others
T28245
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