Tylophorine analog Org-6906 is a potential anticancer and immunosuppressive agent. Org-6906 suppresses the translation of cellular regulatory proteins, including cyclin D1, at the elongation step. Org-6906 allosterically regulates the ATPase and chaperone activities of HSC70 by promoting ATP hydrolysis in the presence of specific RNA binding motifs (AUUUA) of cyclin D1 mRNA.
Molecular Weight:
221.73
CAS Number:
[67384-25-2]
Formula:
C13H16ClN
Target:
Others|||Adrenergic Receptor
T28266
T28266
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